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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Mar 26;40(5):1239–1255. doi: 10.1161/ATVBAHA.120.314139

Figure 6. Microbial choline TMA-lyase inhibitor IMC attenuates choline diet-induced renal tubulointerstitial fibrosis.

Figure 6.

(A) Representative photomicrographs of Masson’s trichrome-stained (scalebar=100 microns), (B) histological scoring of Masson’s trichrome stained kidneys, and (C) correlation between renal histological score and plasma TMAO. Mean scores per mouse ± SEM are shown and global p-value was obtained by 1-way ANOVA (Kruskal-Wallis) and the p-value among the different treatments was determined by 1-way ANOVA (Kruskal-Wallis) after Dunn’s post hoc test and Spearman’s correlation.