Table 5. Experimental Data Used for the Theoretical Solubility Calculation of Individual Components from a Binary System.
temperature
of (K) |
||||
---|---|---|---|---|
component | heat of fusion (kJ/mol) | melting of neat drug | melting of eutectic mix | dissolution test performed |
ibuprofen | 26.82 | 348.75 | 322.06 | 310.15 |
APAP | 59.74 | 442.45 | 404.61 | 310.15 |
caffeine | 22.17 | 510.53 | 404.61 | 310.15 |