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. 2020 Apr 21;5(17):9690–9701. doi: 10.1021/acsomega.9b03886

Table 5. Experimental Data Used for the Theoretical Solubility Calculation of Individual Components from a Binary System.

    temperature of (K)
component heat of fusion (kJ/mol) melting of neat drug melting of eutectic mix dissolution test performed
ibuprofen 26.82 348.75 322.06 310.15
APAP 59.74 442.45 404.61 310.15
caffeine 22.17 510.53 404.61 310.15