Fig. 5.

Gain of hit statistical significance by LAMPA compared to HHsearch. LAMPA hits to region queries, obtained during the QP-specific and AP-specific stages of LAMPA procedure, are compared with matching HHsearch hits to polyprotein queries, in respect to hit Probability (A) and E-value (B); and with matching HHsearch hits to putative domain queries (operational definition, see text for details), in respect to hit Probability (C) and E-value (D). Analyzed HHsearch hits were not subject to post-processing