Table 2. Chronological list of conditional GHR gene disrupted mice.
| Year | Reference | Target Tissue | Inducible | Line Designation | Floxed GHR Line | Cre Line | Stock/Cat. No. |
|---|---|---|---|---|---|---|---|
| 2009 | Fan et al., 2009 ( 4 ) | Liver | - | GHRLD | Sperling | B6.Cg-Tg(Alb-cre)21Mgn/J | JAX: 003574 |
| 2010 | Lu et al., 2010 (25) | Macrophage | - | GHRMacD | Sperling | B6.129P2-Lyz2tm1(cre)Ifo/J | JAX: 004781 |
| 2010 | Mavalli et al., 2010 (33) | Muscle | - | ∆GHR | Sperling | Mef-2c-73kCre+/-/Blk | MGI ID: 3583679 |
| 2011 | Wu et al., 2011 (5) | Beta cell | - | βGHRKO | LeRoith | B6.Cg-Tg(Ins2-cre)25Mgn/J | JAX: 003573 |
| 2012 | Vijayakumar et al., 2012 (34) | Muscle | - | mGHRKO | LeRoith | B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J | JAX: 006475 |
| 2012 | Vijayakumar et al., 2012 (35) | Muscle | - | mGHRKO | LeRoith | B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J | JAX: 006475 |
| 2013 | List et al., 2013 (6) | Fat | - | FaGHRKO | Kopchick | B6.Cg-Tg(Fabp4-cre)1Rev/J | JAX: 005069 |
| 2013 | Vijayakumar et al., 2013 (36) | Muscle | - | mGHRKO | LeRoith | B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J | JAX: 006475 |
| 2013 | Li et al., 2013 (10) | Fat | - | FaGHRKO | Kopchick | B6.Cg-Tg(Fabp4-cre)1Rev/J | JAX: 005069 |
| 2013 | Lu et al., 2013 (26) | Macrophage | - | MacGHR KO† | Sperling | B6.129P2-Lyz2tm1(cre)Ifo/J | JAX: 004781 |
| 2014 | List et al., 2014 (9) | Liver | - | LiGHRKO | Kopchick | B6.Cg-Tg(alb-cre)21Mgn/J | JAX: 003574 |
| 2014 | Fan et al., 2014 (8) | Liver | - | GHRLD | Sperling | 6.Cg-Tg(Alb-cre)21Mgn/J | JAX: 003574 |
| 2014 | Stewart et al., 2014 (28) | HCS | - | Ghrfl/fl;Vav1Cre/+ | LeRoith | Tg(Vav1-cre)1Awr | MGI ID: 3043860 |
| 2015 | Gesing et al., 2015 (11) | Liver | - | LiGHRKO | Kopchick | B6.Cg-Tg(alb-cre)21Mgn/J | JAX: 003574 |
| 2015 | Dominick et al., 2015 (12) | Liver | - | LiGHRKO | Kopchick | B6.Cg-Tg(alb-cre)21Mgn/J | JAX: 003574 |
| 2015 | Zawada et al., 2015 (13) | Liver | - | LiGHRKO | Kopchick | B6.Cg-Tg(alb-cre)21Mgn/J | JAX: 003574 |
| 2015 | List et al., 2015 (37) | Muscle | - | MuGHRKO | Kopchick | B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J | JAX: 006475 |
| 2015 | Cordoba-Chacon et al., 2015 (15) | Liver | Yes | aLivGHRkd | Kopchick | Tail vein injection of Adeno-associated virus-TBGp-Cre | Penn Vector Core: AV-8-PV1091 |
| 2015 | Sadagurski et al., 2015 (14) | Liver | - | LiGHRKO | Kopchick | B6.Cg-Tg(alb-cre)21Mgn/J | JAX: 003574 |
| 2016 | Liu et al., 2016 (29) | Bone | - | DMP-GHRKO | LeRoith | B6.Cg-Tg(Dmp1-cre/ERT2)D77Pdp/J† | JAX: 029594 |
| 2016 | Jara et al., 2016 (30) | Heart | Yes | iC-GHRKO | Kopchick | B6.FVB(129)-A1cfTg(Myh6-cre/Esr1*)1Jmk/J | JAX: 005657 |
| 2016 | Liu et al., 2016 (16) | Liver | - | Li-GHRKO | LeRoith | B6.FVB(129)-Tg(Alb1-cre)1Dlr/J | JAX: 016832 |
| 2016 | Junilla et al., 2016 (32) | Global | Yes | aGHRKO | Kopchick | B6.129-Gt(ROSA)26Sortm1(cre/ERT2)Tyj/J | JAX: 008463 |
| 2017 | Cady et al., 2017 (40) | Brain | - | LeprEYFP∆GHR | Kopchick | B6.129-Leprtm3(cre)Mgmj/J | JAX: 032457 |
| 2019 | List et al., 2019 (20) | Fat | - | AdGHRKO | Kopchick | B6;FVB-Tg(Adipoq-cre)1Evdr/J | JAX: 010803 |
| 2019 | Fang et al., 2019 (7) | Liver | - | Fat-Ghr-/- | Liang | B6;FVB-Tg(Adipoq-cre)1Evdr/J | JAX: 010803 |
| 2019 | Fat | - | L-Ghr-/- | Liang | B6.CgTg(Alb-cre)21Mgn/J | JAX: 003574 | |
| 2019 | Furigo et al., 2019 (41) | Brain | - | AgRP GHR KO | Kopchick | Agrptm1(cre)Lowl/J | JAX: 012899 |
| 2019 | Brain | - | LepR GHR KO | Kopchick | B6.129-Leprtm2(cre)Rck/J | JAX: 008320 | |
| 2019 | Brain | - | Brain GHR KO | Kopchick | B6.Cg-Tg(Nes-cre)1Kln/J | JAX: 003771 | |
| 2019 | Young et al., 2019 (31) | Intestine | - | IntGHRKO | Kopchick | B6.Cg-Tg(Vil1-cre)997Gum/J | JAX: 004586 |
† The name was changed from GHRMacD to MacGHR KO in this paper.