Table 3.

Participants demographics for different subgroups of study

	CN	MCI 1	MCI 2	MCI 3	MCI 4	p	AD
N (% of diagnostic group)	449	404 (58)	230(33)	36 (5.2)	26(3.7)		249
Age, mean (SD)	73.9(5.6)	71.4(7.1)3,4	72.8(7.7)3,4	77.2(5.4)1,2	78.9(5.9)1,2	<.001	74.3(7.9)
Sex-male, %	51.4%	53.2%	67.4%	77.8%	26.9%	<.001	45.4%
Education, mean (SD)	16.3(2.7)	16.2(2.7)2	15.4(3.0)1	15.9(3.2)	15.2(2.9)	.003	15.2(2.9)
Apo E (% e4 carrier)	27.7%	50.1%	52.6%	55.6%	50%	.920	70.4%

P-values are representative of outcomes of analyses of variance (ANOVA) for continuous variables, and Chi-square tests for categorical variables with MCI subgroup membership as the independent variable. MCI subgroup membership as the independent variable. Numbered superscripts denote significant post-hoc differences at p < 0.01 between each aMCI subgroup and the subgroup number indicated