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. 2020 May 7;20:59. doi: 10.1186/s12902-020-0537-2

Table 3.

Genotype frequencies of studied SNPs of the KISS1 gene, in PCOS patients and controls

SNPs Genotypes Frequency OR (95%CI) χ2 p-value
PCOS patients n (%) Controls n (%) Total n (%)
rs372790354 G/A GG 86 (82.7%) 92 (84.4%) 178 (83.6%) Reference
GA 13 (12.5%) 17 (15.6%) 30 (14.1%) 0.07 (0.01–1.38) 5.51 0.018*
AA 5 (4.8%) 0 (0.0%) 5 (2.3%) 1.17 (0.64–215) 5.20 0.022*
Total 104 (100.0%) 109 (100.0%) 213 (100.0%)
rs12998 G/A GG 87 (83.7%) 88 (80.7%) 175 (82.2%) Reference
GA 12 (11.5%) 17 (15.6%) 29 (13.6%) 0.56 (0.13–2.55) 0.56 0.454
AA 5 (4.8%) 4 (3.7%) 9 (4.2%) 1.26 (0.33–4.86) 0.12 0.732
Total 104 (100.0%) 109 (100.0%) 213 (100.0%)
rs35431622 A/T AA 97 (93.3%) 101 (92.7%) 198 (92.96%) Reference
AT 7 (6.7%) 8 (7.3%) 15 (7.04%) 0.91 (0.32–2.61) 0.03 0.862
TT 0 (0.0%) 0 (0.0%) 0 (0.0%)
Total 104 (100.0%) 109 (100.0%) 213 (100.0%)

*Significant, p values refer to Chi-Square (χ2) test, OR odds ratio, CI confidence interval