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. 2020 May 6;15:45. doi: 10.1186/s13000-020-00964-6

Table 9.

Comparison of estimated reagent cost of Nanopore workflow (24-plex) and randomly-selected prices of HPV genotyping referral service in Hong Kong

This study
Procedure Number of specimens Cost
DNA extraction and PCRs 201 patients +20 controls = 221 USD 20.02 × 221 reactions = USD 4424.42
Nanopore sequencing

115 patients / 24 = at least 5 runs

N = 120 for 1 positive control per run

USD 1155.94 × 5 runs = USD 5779.70
Cost per patient specimen (4424.42 + 5779.70) / 201 = USD 50.77
Referral service (transportation cost not included)
Lab A USD 77.19
Lab B USD 124.79
Lab C USD 101.63
Lab D USD 120.93
Average USD 106.14