Fig. 1.

Circulating miRNAs exhibit alterations in expression in asthma subgroups. Expression of six candidate miRNAs (a-f) were examined in blood serum from individuals with asthma on inhaled corticosteroids and with eosinophilia. Allergic asthmatic individuals (AA) and non-allergic asthmatics (NAA) had high levels of circulating eosinophils (> 0.4 × 10^9 cells/L) and healthy subjects had low levels of circulating eosinophils (< 0.1 × 10^9 cells/L). Each dot is equivalent to one subject. Healthy = 24, AA = 9, NAA = 13. Expression is shown as 2^-dCt. Kruskal-Wallis followed by Dunns post-test was performed. p < 0.05 = *; p < 0.01 = **; p < 0.001 = ***