Table 2.
The effect of miR-637 on blood lipids in ApoE knockout mice ()
| Group | AG-NC | AG | AN-NC | AN |
|---|---|---|---|---|
| Body weight (g) | 26.48 ± 2.54 | 28.37 ± 2.88 | 27.52 ± 2.33 | 28.12 ± 2.42 |
| TG (mmol/l) | 2.46 ± 0.55 | 1.86 ± 0.52& | 2.42 ± 0.62 | 3.82 ± 0.62*** |
| TC (mmol/l) | 14.78 ± 2.96 | 11.34 ± 2.21&& | 15.32 ± 2.89 | 17.11 ± 3.82* |
| HDL-C (mmol/l) | 3.44 ± 0.87 | 5.12 ± 0.95&&& | 3.47 ± 0.78 | 2.35 ± 0.89* |
| LDL-C (mmol/l) | 12.01 ± 1.12 | 10.12 ± 1.08&& | 11.90 ± 1.32 | 14.78 ± 2.76** |
n = 10; AG-NC miR-637 agomir negative control; AG miR-637 agomir, AN-NC miR-637 antagomir negative control, AN miR-637 antagomir, TG Triglyceride, TC Total cholesterol, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol
&, && and &&&& respectively indicate p < 0.05, p < 0.01 and p < 0.001
*, ** and *** respectively indicate p < 0.05, p < 0.01 and p < 0.001