. 2020 Apr 24;5(17):10145–10159. doi: 10.1021/acsomega.0c00865

Table 3. E. coli DNA Gyrase IC₅₀ and Binding Thermodynamic Parameters of 8-Methylamino-2-Quinolinone Derivatives to GyrB.

IC₅₀ values are reported from the means of at least two independent experiments.

Values are the means of at least three separate experiments.

IC₅₀ ratio (8-H/8-NHMe).

Table 3. E. coli DNA Gyrase IC50 and Binding Thermodynamic Parameters of 8-Methylamino-2-Quinolinone Derivatives to GyrB.