Table 2. SAXS Modified Core–Shell Model Fit Results of ALGN-Graft-PLGA and SLGN-Graft-PLGA Polymeric Nanoparticles.
| polymer (w/w) | particle diameter (=core + 2*shell) | core diameter (nm) ± S.D. | shell thickness (nm) ± S.D. | polydispersity % |
|---|---|---|---|---|
| ALGN-graft-PLGA 1:2 | 82 ± 2 | 77 ± 2 | 2.2 ± 0.1 | 36 ± 3 |
| ALGN-graft-PLGA 1:4 | 86 ± 2 | 82 ± 2 | 1.8 ± 0.1 | 36 ± 4 |
| ALGN-graft-PLGA 1:6 | 412a | 252.0a | 80.0a | 30 ± 3 |
| SLGN-graft-PLGA 1:2 | 120 ± 3 | 78 ± 2 | 20.0 ± 0.3 | 40 ± 4 |
| SLGN-graft-PLGA 1:4 | 136 ± 4 | 124 ± 2 | 6.0 ± 1 | 30 ± 3 |
| SLGN-graft-PLGA 1:6 | 208a | 182.4a | 13a | 20 ± 2 |
a
Note: estimated minimum diameter from SAXS, as the particle diameter value cannot be determined.