Table 2.
Factors explaining the variation in microbiota composition between samples as determined by redundancy analysis. Factors significantly explaining the variation are shown
| Control | ST | LT | ALL | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Factor | Explains (%) | FDR p-value | Factor | Explains (%) | FDR p-value | Factor | Explains (%) | FDR p-value | Factor | Explains (%) | FDR p-value |
| Vaginal delivery | 7.7 | 0.00433 | Postnatal age | 7.4 | 0.01533 | Postnatal age | 7.8 | 0.016 | Postnatal age | 5.5 | 0.006 |
| Postnatal age | 5.5 | 0.00433 | PROM No | 5.4 | 0.01533 | Vaginal delivery | 6.9 | 0.016 | AB1 duration | 2.5 | 0.006 |
| Primary c-section | 3.2 | 0.00433 | PROM Yes | 5.4 | 0.01533 | TPN (days) | 6.5 | 0.016 | Female | 2.9 | 0.006 |
| Secondary c-section | 3.2 | 0.00433 | Male | 4.9 | 0.01533 | Male | 2.9 | 0.006 | |||
| Days until FEF | 3.0 | 0.00433 | Female | 4.9 | 0.01533 | Days until FEF | 2.2 | 0.006 | |||
| HM_6weeks (%) | 2.9 | 0.00433 | Primary c-section | 2.0 | 0.006 | ||||||
| Female | 2.7 | 0.00433 | GA (weeks) | 1.5 | 0.006 | ||||||
| Male | 2.7 | 0.00433 | |||||||||
| CPAP Yes | 2.3 | 0.00743 | |||||||||
| CPAP No | 2.3 | 0.00743 | |||||||||
| No Maternal AB | 1.6 | 0.02022 | |||||||||
| Maternal AB | 1.6 | 0.02022 | |||||||||
| GA (weeks) | 1.6 | 0.02022 |
Abbreviations: FDR: false discovery rate, C-section: caesarean section, FEF: full enteral feeding, HM: human milk, CPAP: continuous positive airway pressure, AB: antibiotics, GA: gestational age, PROM: prolonged rupture of membranes, TPN: total parenteral nutrition