Table 2.
Multivariate analyses of MSSCC
| Characteristic | OS | P Value | DFS | P Value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Smoking | ||||
| No | [Reference] 1 | [Reference] 1 | ||
| Yes | 2.098(1.140–3.862) | 0.017* | NA | 0.377 |
| Differentiation | ||||
| Highly | [Reference] 1 | [Reference] 1 | ||
| Medium | 1.784 (0.936–3.398) | 0.078 | 1.648(0.909–2.988) | 0.1 |
| Low | 3.473 (1.793–6.725) | < 0.001* | 2.970(1.597–5.524) | 0.001* |
| T stage | ||||
| T1 | [Reference] 1 | [Reference] 1 | ||
| T2 | 0.711 (0.277–1.824) | 0.479 | NA | 0.336 |
| T3 | 0.439 (0.146–1.325) | 0.144 | NA | 0.928 |
| T4 | 2.454 (1.099–5.477) | 0.028* | NA | 0.059 |
| N stage | ||||
| N0 | [Reference] 1 | [Reference] 1 | ||
| N1 | NA | 0.192 | 3.400(1.068–10.828) | 0.038* |
| N2 | NA | 0.148 | 1.742(0.738–4.116) | 0.205 |
| M stage | ||||
| M0 | [Reference] 1 | [Reference] 1 | ||
| M1 | NA | 0.248 | NA | 0.046 |
| Clinical stage | ||||
| I | [Reference] 1 | [Reference] 1 | ||
| II | NA | 0.346 | NA | 0.883 |
| III | NA | 0.267 | NA | 0.798 |
| IV | NA | 0.663 | NA | 0.167 |
| Treatment | ||||
| SUR | [Reference] 1 | [Reference] 1 | ||
| SUR+CT/RT | 0.853 (0.319–2.270) | 0.751 | 0.852(0.336–2.161) | 0.736 |
| CT/RT+SUR | 0.369 (0.107–1.267) | 0.113 | 0.510(0.167–1.551) | 0.235 |
| NON-SUR | 1.054 (0.381–2.919) | 0.919 | 0.910(0.315–2.362) | 0.846 |
HR hazard ratio, CI confidence interval, NA not applicable
*Statistical significance