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. 2020 May 7;39:79. doi: 10.1186/s13046-020-01589-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — SNCG is overexpressed in EOC tissue and correlated with poor prognosis in patients with HGSOC. a IHC staining showed SNCG expression in the normal ovary, fallopian tube tissues, benign tumor, and borderline tumor (original magnification, × 200). b Representative images of IHC staining of SNCG expression in different pathological types of EOC tissues (original magnification, upper× 200, lower×400). c Kaplan-Meier analysis was performed for EOC patients to analyze the association between SNCG expression and survival outcome (OS and PFS). d In the HGSOC cohort, Kaplan-Meier analysis indicated the correlation of SNCG overexpression with OS (upper) and PFS (lower). By multivariate Cox regression analysis (Forest plot), results showed that SNCG overexpression was an independent prognostic factor