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. 2020 May 7;19:84. doi: 10.1186/s12943-020-01191-9

Fig. 2.

Fig. 2

Elevated circ_0020710 promotes melanoma progression. a The efficacy of circ_0020710 interference and overexpression was analyzed by qRT-PCR. b Colony formation assay was used to detect the proliferation ability of melanoma cells with different treatments. c CCK-8 assay was performed to detect the proliferation of melanoma cells. d Transwell invasion assay was used to detect the invasion ability of melanoma cells following different treatments. e Wound healing migration assay was performed to detect the migration ability of melanoma cells with different treatments. Unpaired student’s t-test, Mann-Whitney U test, Kruskal-Wallis test and one-way ANOVA test were used for the statistical analyses. *p < 0.05; **p < 0.01; ***p < 0.001