Figure 4.

Firing rate modulation of SC neurons during the detection task. A, Normalized spike rates of all recorded SC neurons from two mice aligned on the onset of contralateral orientation changes (12°). Each row shows the normalized spike counts in 10-ms bins from an individual neuron. Neurons (n = 260) are sorted by recording depth from the most superficial (top) to the deepest (bottom). B, SC depth for each of the neurons, following the same sorting convention as in A. C, Mean firing rate across all SC neurons. Solid line indicates the mean, and shaded region indicates ±SEM. Vertical blue shaded regions indicate the three temporal epochs chosen for the SC inhibition experiment. Inset, Distribution of reaction times across all recording sessions; dashed line indicates the median.