Table 3.
Downregulated proteins with signal transduction function in GO analysis (fold change >1.5, p < 0.05).
| Id | Accession | Gene name | Description |
|---|---|---|---|
| TNR5_HUMAN | P25942 | CD40 | Tumor necrosis factor receptor superfamily member 5 |
| NPM_HUMAN | P06748 | NPM1 | Nucleophosmin |
| TNR6_HUMAN | P25445 | FAS | Tumor necrosis factor receptor superfamily member 6 |
| IF16_HUMAN | Q16666 | IFI16 | Gamma-interferon-inducible protein 16 |
| BID_HUMAN | P55957 | BID | BH3-interacting domain death agonist |
| E9PCH4_HUMAN | E9PCH4 | Uncharacterized protein | |
| DAP1_HUMAN | P51397 | DAP | Death-associated protein 1 |
| CNBP1_HUMAN | Q9NSA3 | CTNNBIP1 | Beta-catenin-interacting protein 1 |
| ASPH_HUMAN | Q12797 | ASPH | Aspartyl/asparaginyl beta-hydroxylase |
| A4_HUMAN | P05067 | APP | Amyloid-beta A4 protein |
| GNAQ_HUMAN | P50148 | GNAQ | Guanine nucleotide-binding protein G(q) subunit alpha |
| K2C8_HUMAN | P05787 | KRT8 | Keratin, type II cytoskeletal 8 |
| SP110_HUMAN | Q9HB58 | SP110 | Sp110 nuclear body protein |
| SDC4_HUMAN | P31431 | SDC4 | Syndecan-4 |
| CO1A2_HUMAN | P08123 | COL1A2 | Collagen alpha-2(I) chain |
| HNRDL_HUMAN | O14979 | HNRNPDL | Heterogeneous nuclear ribonucleoprotein D-like |
| CAB39_HUMAN | Q9Y376 | CAB39 | Calcium-binding protein 39 |
| ERLN2_HUMAN | O94905 | ERLIN2 | Erlin-2 |
| CY24 A_HUMAN | P13498 | CYBA | Cytochrome b-245 light chain |
| SLK_HUMAN | Q9H2G2 | SLK | STE20-like serine/threonine-protein kinase |
| CGL_HUMAN | P32929 | CTH | Cystathionine gamma-lyase |
| F5H6H0_HUMAN | F5H6H0 | HMGA2 | High-mobility group protein HMGI-C |
| SKI_HUMAN | P12755 | SKI | Ski oncogene |
| BI2L1_HUMAN | Q9UHR4 | BAIAP2L1 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 |
| RHG19_HUMAN | Q14CB8 | ARHGAP19 | Rho GTPase-activating protein 19 |
| PTEN_HUMAN | P60484 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
| CCNA2_HUMAN | P20248 | CCNA2 | Cyclin-A2 |
| PARK7_HUMAN | Q99497 | PARK7 | Protein/nucleic acid deglycase DJ-1 |
| APOE_HUMAN | P02649 | APOE | Apolipoprotein E |
| IKKA_HUMAN | O15111 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha |
| RO52_HUMAN | P19474 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 |
| RWDD1_HUMAN | Q9H446 | RWDD1 | RWD domain-containing protein 1 |
| AATC_HUMAN | P17174 | GOT1 | Aspartate aminotransferase, cytoplasmic |
| ZFY27_HUMAN | Q5T4F4 | ZFYVE27 | Protrudin |
| SPTN2_HUMAN | O15020 | SPTBN2 | Spectrin beta chain, nonerythrocytic 2 |
| SRPRB_HUMAN | Q9Y5M8 | SRPRB | Signal recognition particle receptor subunit beta |
| KBTB7_HUMAN | Q8WVZ9 | KBTBD7 | Kelch repeat and BTB domain-containing protein 7 |
| DDX54_HUMAN | Q8TDD1 | DDX54 | ATP-dependent RNA helicase DDX54 |
| A0A0B4J1V8_HUMAN | A0A0B4J1V8 | PPAN-P2RY11 | HCG2039996 |
| STAT2_HUMAN | P52630 | STAT2 | Signal transducer and activator of transcription 2 |
| ITPR3_HUMAN | Q14573 | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3 |
| TM109_HUMAN | Q9BVC6 | TMEM109 | Transmembrane protein 109 |
| K7EM85_HUMAN | K7EM85 | ARHGAP45 | Rho GTPase-activating protein 45 |
| IDE_HUMAN | P14735 | IDE | Insulin-degrading enzyme |
| RADI_HUMAN | P35241 | RDX | Radixin |
| SEM7A_HUMAN | O75326 | SEMA7A | Semaphorin-7A |
| RHG24_HUMAN | Q8N264 | ARHGAP24 | Rho GTPase-activating protein 24 |
| ERLN1_HUMAN | O75477 | ERLIN1 | Erlin-1 |