Table 3.
Univariate and multivariate logistic regression about laboratory parameters in patients with sepsis.
| Parameters | Training set (n = 819) | Validation set (n = 454) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Univariate logistic analysis | Multivariate logistic analysis | Univariate logistic analysis | Multivariate logistic analysis | |||||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
| Complications | ||||||||||
| Respiratory failure | 1.439 (1.235, 1.676) | <0.001 | 1.338 (1.137, 1.574) | <0.001 | 1.626 (1.299, 2.036) | <0.001 | 1.426 (1.056, 1.925) | 0.020 | ||
| Shock | 1.471 (1.236, 1.751) | <0.001 | 1.292 (1.066, 1.566) | 0.009 | 1.894 (1.523, 2.354) | <0.001 | ||||
| Gastrointestinal disorder | 1.396 (1.007, 1.935) | 0.046 | 2.149 (1.638, 2.820) | <0.001 | 1.454 (1.014, 2.086) | 0.042 | ||||
| Acute kidney injury | 1.433 (1.054, 1.947) | 0.022 | 2.403 (1.674, 3.448) | <0.001 | 1.766 (1.127, 2.767) | 0.013 | ||||
| Heart failure | 1.475 (1.071, 2.033) | 0.017 | 2.012 (1.355, 2.986) | <0.001 | 1.626 (1.007, 2.624) | 0.047 | ||||
| Disturbance of consciousness | 1.627 (1.219, 2.171) | 0.001 | 1.580 (1.165, 2.144) | 0.003 | 3.829 (2.592, 5.657) | <0.001 | 3.342 (2.164, 5.161) | <0.001 | ||
| Biochemical parameters | ||||||||||
| Lac | 1.417 (1.302, 1.542) | <0.001 | 1.346 (1.217, 1.489) | <0.001 | 1.487 (1.329, 1.664) | <0.001 | 1.274 (1.126, 1.442) | <0.001 | ||
| PT | 1.110 (1.057, 1.165) | <0.001 | 1.183 (1.094, 1.280) | <0.001 | ||||||
| APTT | 1.017 (1.008, 1.025) | <0.001 | 1.008 (1.001, 1.016) | 0.028 | ||||||
| Fibrinogen | 0.586 (0.488, 0.703) | <0.001 | 0.767 (0.628, 0.937) | 0.009 | 0.412 (0.315, 0.538) | <0.001 | 0.619 (0.435, 0.880) | 0.008 | ||
| DBIL | 1.014 (1.005, 1.023) | 0.002 | 1.026 (1.010, 1.042) | 0.002 | ||||||
| γ-GT | 1.003 (1.000, 1.005) | 0.040 | 1.009 (1.004, 1.014) | <0.001 | ||||||
| BUN | 1.059 (1.026, 1.092) | <0.001 | 1.203 (1.090, 1.327) | <0.001 | ||||||
| PLT | 0.994 (0.992, 0.996) | <0.001 | 0.990 (0.987, 0.993) | <0.001 | ||||||
Lac: lactate; PT: prothrombin time; APTT: activated partial thromboplastin time; DBIL: direct bilirubin; γ-GT: γ-glutamyl transpeptidase; BUN: blood urea nitrogen; PLT: platelet.