Table 2.
Adjusted odds ratio (OR) with 95% confidence interval (CI) and p value for selected tumor and demographic characteristics as indicators of metastatic diseases among GIST patients.
| Characteristics | OR | 95% CI | p value |
|---|---|---|---|
| Gender | 0.124 | ||
| Female | Reference | 1.000 | |
| Male | 1.146 | 0.963-1.363 | 0.124 |
| Insurance | 0.094 | ||
| Yes | Reference | 1.000 | |
| No | 1.475 | 0.944-2.305 | 0.088 |
| NOS | 0.878 | 0.706-1.092 | 0.244 |
| Tumor location | 0.001 | ||
| Large intestine | Reference | 1.000 | |
| Peritoneum | 2.185 | 1.156-4.131 | 0.016 |
| Stomach | 1.823 | 1.163-2.855 | 0.009 |
| Small intestine | 2.564 | 1.607-4.092 | <0.001 |
| Esophagus | 1.445 | 0.293-7.120 | 0.651 |
| Pathologic grade | <0.001 | ||
| I | Reference | 1.000 | |
| II | 1.071 | 0.646-1.774 | 0.791 |
| III | 2.518 | 1.495-4.241 | 0.001 |
| IV | 2.798 | 1.721-4.551 | <0.001 |
| NOS | 1.859 | 1.247-2.771 | 0.002 |
| Tumor size (cm) | <0.001 | ||
| ≤2 | Reference | 1.000 | |
| 2-5 | 2.366 | 1.353-4.138 | 0.003 |
| 5-10 | 3.516 | 2.040-6.060 | <0.001 |
| >10 | 5.370 | 3.110-9.272 | <0.001 |
| NOS | 7.124 | 4.005-12.671 | <0.001 |
| Lymph nodes | <0.001 | ||
| Negative | Reference | 1.000 | |
| Positive | 6.153 | 4.531-8.355 | <0.001 |
| NOS | 3.991 | 3.035-5.249 | <0.001 |
| Extension | <0.001 | ||
| Mild | Reference | 1.000 | |
| Grievous | 2.886 | 2.368-3.518 | <0.001 |
| NOS | 3.991 | 3.035-5.249 | <0.001 |
| Mitotic count | <0.001 | ||
| ≤5/50 HPF | Reference | 1.000 | |
| >5/50 HPF | 1.554 | 1.207-2.000 | 0.001 |
| NOS | 1.788 | 1.348-2.372 | <0.001 |
NOS: not otherwise specified.