Table 2.
Different intranetwork FCs of RSNs between two groups.
| Condition | RSN | Brain regions | BA | Peak t scores | MNI coordinates (x, y, z) | Cluster size (voxels) |
|---|---|---|---|---|---|---|
| DR < HC | BGN | B-THA | — | -4.0477 | 3, -21, 12 | 121 |
| R-CAU | — | -4.9691 | 18, -12, 24 | 182 | ||
| DR < HC | VN | B-MOG | 17, 18 | -5.4465 | -15, -96, 0 | 1497 |
| DR < HC | vDMN | B-PreCUN | — | -4.4778 | 3, -24, 30 | 562 |
| DR < HC | rECN | R-IPL | 40 | -3.8525 | 45, -57, 57 | 155 |
| L-IPL | 40 | -5.6977 | -45, -69, 48 | 181 | ||
| L-SMFG | 8 | -3.3675 | 9, 36, 51 | 96 | ||
| DR < HC | SN | B-ACC | 24 | -4.1853 | 3, 21, 24 | 133 |
| DR < HC | lECN | L-SFG | 8 | -3.7062 | -15, 45, 42 | 78 |
| DR < HC | AN | L-STG | 42 | -4.7819 | -66, -30, 15 | 263 |
| R-STG | 40 | -4.3684 | 60, -24, 15 | 165 | ||
| DR < HC | dDMN | L-PCC | — | -4.2416 | 3, -63, 3 | 94 |
| L-SMFG | 8 | -4.082 | 0, 39, 57 | 83 |
Note: the statistical threshold was set at the voxel level with P < 0.01 for multiple comparisons using Gaussian random field theory (voxel-level P < 0.01, GRF correction, cluster-level P < 0.05). t score represents the statistical value of peak voxel showing the differences in FC between the two groups. Abbreviations: DR: diabetic retinopathy; HC: healthy control; FC: functional connectivity; RSNs: resting-state networks; BA: Brodmann area; MNI: Montreal Neurologic Institute; BGN: basal ganglia network; VN: visual network; vDMN: ventral default mode network; rECN: right executive control network; SN: salience network; lECN: left executive control network; AN: auditory network; dDMN: dorsal default mode network; RSN: resting-state networks; THA: thalamus; CAU: caudate; MOG: middle occipital gyrus; PreCUN: precuneus; IPL: inferior parietal lobule; SMFG: superior medial frontal gyrus; ACC: anterior cingulate gyrus; SFG: superior frontal gyrus; STG: superior temporal gyrus; PCC: posterior cingulate gyrus; GRF: Gaussian random field; L: left; R: right; B: bilateral.