Table 4.
The summary of the results from different comparative genetic models in different diseases.
| Diseases | Genetic models | I 2 (%) | P I | Effects model | OR (95% CI) | Z | P z | Egger's regression analysis | P E | Begg's regression analysis | P B |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA | C/G | 0 | 0.51 | FIX | 1.16 (1.03, 1.31) | 2.37 | 0.02 | -1.76 | 0.18 | -0.98 | 0.33 |
| CC/GG | 0 | 0.96 | FIX | 1.43 (0.95, 2.14) | 1.72 | 0.09 | -0.40 | 0.75 | -0.49 | 0.62 | |
| GC/GG | 13.5 | 0.33 | FIX | 1.12 (0.99, 1.28) | 1.76 | 0.08 | -1.87 | 0.14 | -1.47 | 0.14 | |
| CC+GC/GG | 11.9 | 0.34 | FIX | 1.20 (1.01, 1.43) | 2.12 | 0.03 | -2.03 | 0.13 | -0.98 | 0.33 | |
| CC/GC+GG | 0 | 0.98 | FIX | 1.38 (0.92, 2.07) | 1.53 | 0.13 | -0.06 | 0.95 | 0 | 1.00 | |
|
| |||||||||||
| UC | C/G | 32 | 0.23 | FIX | 1.22 (1.00, 1.47) | 1.99 | 0.05 | 5.19 | 0.21 | 1.57 | 0.12 |
| CC/GG | 0 | 0.47 | FIX | 1.86 (0.98, 3.50) | 1.91 | 0.06 | -0.49 | 0.89 | -0.52 | 0.60 | |
| GC/GG | 51.6 | 0.13 | FIX | 1.11 (0.91, 1.38) | 1.50 | 0.14 | 4.85 | 0.44 | 0.52 | 0.60 | |
| CC+GC/GG | 29.3 | 0,24 | FIX | 1.15 (0.96, 1.38) | 1.50 | 0.14 | 5.74 | 0.10 | 1.57 | 0.12 | |
| CC/GC+GG | 0 | 0.39 | FIX | 1.93 (1.01, 3.01) | 1.99 | 0.05 | -1.23 | 0.77 | -0.52 | 0.60 | |
|
| |||||||||||
| CD | C/G | 0 | 0.58 | FIX | 1.23 (1.04, 1.47) | 2.40 | 0.02 | 1.14 | 0.53 | 1.57 | 0.12 |
| CC/GG | 0 | 0.49 | FIX | 1.22 (0.64, 2.33) | 0.60 | 0.55 | 2.66 | 0.13 | 1.57 | 0.12 | |
| GC/GG | 0 | 0.54 | FIX | 1.32 (1.11, 1.57) | 3.14 | 0.01 | -0.19 | 0.92 | -0.52 | 0.60 | |
| CC+GC/GG | 0 | 0.68 | FIX | 1.30 (1.10, 1.52) | 3.09 | 0.01 | 0.24 | 0.90 | 0.52 | 0.60 | |
| CC/GC+GG | 0 | 0.42 | FIX | 1.14 (0.59, 2.18) | 0.38 | 0.7 | 2.53 | 0.24 | 0.52 | 0.60 | |
|
| |||||||||||
| AIH | C/G | 0 | 0.40 | FIX | 1.03 (0.73, 1.45) | 0.17 | 0.86 | -6.57 | 0.03 | -1.57 | 0.12 |
| CC/GG | 0 | 0.97 | FIX | 1.86 (0.40, 8.75) | 0.79 | 0.43 | 0.31 | 0.87 | -0.52 | 0.60 | |
| GC/GG | 39.8 | 0.19 | FIX | 0.93 (0.67, 1.29) | 0.43 | 0.67 | -10.62 | 0.04 | -1.57 | 0.12 | |
| CC+GC/GG | 27.4 | 0.25 | FIX | 0.98 (0.71, 1.33) | 0.16 | 0.87 | -9.52 | 0.01 | -1.57 | 0.12 | |
| CC/GC+GG | 0 | 0.95 | FIX | 1.98 (0.42, 9.32) | 0.87 | 0.39 | 1.39 | 0.61 | 0.52 | 0.60 | |
|
| |||||||||||
| AD | C/G | 0 | 0.52 | FIX | 1.41 (1.13, 1.76) | 3.03 | 0.01 | 2.37 | ____ | 1.00 | 0.32 |
| CC/GG | 0 | 0.62 | FIX | 3.21 (1.44, 7.18) | 2.84 | 0.01 | 3.42 | ____ | 1.00 | 0.32 | |
| GC/GG | 0 | 0.60 | FIX | 1.21 (0.96, 1.52) | 1.6 | 0.11 | 1.67 | ____ | 1.00 | 0.32 | |
| CC+GC/GG | 0 | 0.67 | FIX | 1.29 (1.04, 1.59) | 2.38 | 0.02 | 2.02 | ____ | 1.00 | 0.32 | |
| CC/GC+GG | 0 | 0.65 | FIX | 3.03 (1.34, 6.83) | 2.67 | 0.01 | 3.02 | ____ | 1.00 | 0.32 | |
|
| |||||||||||
| AP | C/G | 0 | 0.39 | FIX | 1.59 (1.28, 1.98) | .12 | 0.01 | 18.13 | ____ | 1.00 | 0.32 |
| CC/GG | 9.7 | 0.29 | FIX | 1.88 (1.25, 2.82) | 3.03 | 0.01 | 10.79 | ____ | 1.00 | 0.32 | |
| GC/GG | 0 | 0.46 | FIX | 1.22 (0.89, 1.68) | 1.21 | 0.23 | 82.99 | ____ | 1.00 | 0.32 | |
| CC+GC/GG | 0 | 0.57 | FIX | 1.26 (1.05, 1.51) | 2.40 | 0.02 | 8.90 | ____ | 1.00 | 0.32 | |
| CC/GC+GG | 0 | 0.61 | FIX | 2.60 (1.55, 4.37) | 3.60 | 0.01 | 15.55 | ____ | 1.00 | 0.32 | |
|
| |||||||||||
| HSPN | C/G | 0 | 0.78 | FIX | 1.65 (1.33, 2.05) | 4.54 | 0.01 | 8.39 | ____ | 1.00 | 0.32 |
| CC/GG | 0 | 0.70 | FIX | 2.03 (1.32, 3.12) | 3.21 | 0.01 | 7.45 | ____ | 1.00 | 0.32 | |
| GC/GG | 0 | 0.87 | FIX | 1.15 (0.82, 1.61) | 0.81 | 0.42 | 34.18 | ____ | 1.00 | 0.32 | |
| CC+GC/GG | 0 | 0.97 | FIX | 1.27 (1.06, 1.53) | 2.63 | 0.01 | 4.63 | ____ | 1.00 | 0.32 | |
| CC/GC+GG | 0 | 0.88 | FIX | 2.88 (1.72, 4.83) | 4.02 | 0.01 | 7.69 | ____ | 1.00 | 0.32 | |