Table 2.
Patient characteristics for the cohorts covered by the three normalization methods. Diagnoses are coded in International Classification of Diseases version 10
| Normalization method | DDD n (%) | Olanzapine equivalents n (%) | Chlorpromazine equivalents n (%) |
|---|---|---|---|
| Number of patients | 1589 | 1539 | 438 |
| Male sex | 1043 (65.6) | 1010 (65.6) | 287 (65.5) |
| Mean age in years (SD) | 40.3 (6.3) | 40.1 (6.4) | 40.1 (6.3) |
| Diagnoses | |||
| F10 Alcohol related disorders | 666 (41.9) | 645 (41.9) | 149 (34.0) |
| F11 Opioid related disorders | 266 (16.7) | 256 (16.6) | 66 (15.1) |
| F12 Cannabis related disorders | 476 (30.0) | 458 (29.8) | 130 (29.7) |
| F13 Sedative, hypnotic, or anxiolytic related disorders | 255 (16.0) | 247 (16.0) | 57 (13.0) |
| F14 Cocaine related disorders | 189 (11.9) | 182 (11.8) | 41 (9.4) |
| F15 Other stimulant related disorders | 126 (7.9) | 122 (7.9) | 28 (6.4) |
| F19 Other psychoactive substance related disorders | 225 (14.2) | 218 (14.2) | 60 (13.7) |
| F20 Schizophrenia | 740 (46.6) | 707 (45.9) | 197 (45.0) |
| F21 Schizotypal disorder | 105 (6.6) | 103 (6.7) | 28 (6.4) |
| F22 Delusional disorder | 56 (3.5) | 54 (4.9) | 20 (4.6) |
| F23 Brief psychotic disorder | 25 (1.6) | 25 (1.6) | 10 (2.3) |
| F25 Schizoaffective disorder | 50 (3.1) | 49 (4.9) | 13 (3.0) |
| F31 Bipolar disorder | 98 (6.2) | 97 (6.3) | 26 (5.9) |
| F32 Mayor depressive disorder, single episode | 120 (7.6) | 119 (7.7) | 18 (4.1) |
| F33 Mayor depressive disorder, recurrent | 197 (12.4) | 193 (12.5) | 40 (9.1) |
| F41 Other anxiety disorders | 162 (10.2) | 159 (10.3) | 33 (7.5) |
| F60 Specific personality disorders | 329 (20.7) | 325 (21.1) | 80 (18.3) |
| Z046 Encounter for general psychiatric examination, requested by authority | 266 (16.7) | 250 (16.2) | 66 (15.1) |