Table 2.
Prevalence of genotypes of the three polymorphisms (LTF, ENAM and AMELX)
| First author, publication year |
LTF rs1126478a |
ENAM s1264848a |
ENAM rs3796704a |
ENAM rs3796703b | P-value of HWE for controls | ||||
|---|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | Case | Control | ||
| Ouryouji, 2008 [13] | NA | NA | NA | NA | NA | NA | 76/4/0 | 59/8/0 | 0.603 |
| Azevedo, 2010 [16] | 16/30/16 | 19/22/7 | NA | NA | NA | NA | NA | NA | 0.877 |
| Jeremias, 2013 [11] | NA | NA | 13/44/20 | 21/41/20 | 4/11/61 | 1/19/57 | NA | NA | 0.999/0.676 |
| Ergöz, 2014 [19] | NA | NA | 4/41/55 | 1/35/64 | 0/16/78 | 1/27/69 | NA | NA | 0.108/0.351 |
| Volckova, 2014 [20] | 288/150/44 | 86/56/13 | NA | NA | NA | NA | NA | NA | 0.374 |
| Gerreth, 2016 [14] | NA | NA | 8/37/3 | 4/26/18 | NA | NA | NA | NA | 0.202 |
| Wang, 2017 [5] | 64/222/219 | 64/209/227 | NA | NA | NA | NA | 439/64/2 | 458/42/0 | 0.149/0.327 |
| Borilova Linhartova, 2018 [22] | NA | NA | 45/259/237 | 19/74/84 | NA | NA | NA | NA | 0.656 |
| Koohpeima, 2018 [23] | NA | NA | NA | NA | 0/32/204 | 0/20/146 | NA | NA | 0.409 |
| Wang, 2018 [24] | 63/224/220 | 51/168/184 | NA | NA | NA | NA | NA | NA | 0.196 |
| Devang Divakar, 2019 [25] | NA | NA | 89/58/21 | 116/68/9 | 11/58/99 | 25/76/92 | NA | NA | 0.809/0.146 |
| First author, publication year | AMELX rs946252b | AMELX rs17878486b | AMELX rs6639060b | AMELX rs2106416b | P-value of HWE for controls | ||||
| Case | Control | Case | Control | Case | Control | Case | Control | ||
| Ouryouji, 2008 [13] | NA | NA | NA | NA | 80/0/0 | 67/0/0 | 78/2/0 | 16/6/0 | NA/0.458 |
| Kang, 2011 [17] | NA | NA | 1/2/82 | 0/2/29 | NA | NA | NA | NA | 0.852 |
| Olszowski, 2012 (i) [18] | NA | NA | NA | NA | NA | NA | 24/13/0 | 21/12/1 | 0.643 |
| Olszowski, 2012 (ii) [18] | NA | NA | NA | NA | NA | NA | 26/26/6 | 28/20/2 | 0.495 |
| Gasse, 2013 [12] | 5/9/25 | 4/1/25 | NA | NA | NA | NA | NA | NA | < 0.0001 |
| Jeremias, 2013 [11] | 61/12/5 | 63/13/5 | 4/15/57 | 15/11/56 | NA | NA | NA | NA | 0.002/< 0.0001 |
| Ergöz, 2014 [19] | 5/18/11 | 10/17/9 | 8/18/14 | 3/21/8 | NA | NA | NA | NA | 0.742/0.051 |
| Yildiz, 2016 [21] | NA | NA | NA | NA | 54/11/12 | 56/9/12 | NA | NA | < 0.0001 |
| Gerreth, 2017 [15] | NA | NA | 8/10/30 | 31/14/3 | NA | NA | NA | NA | 0.422 |
Abbreviations: LTF Lactotransferrin, ENAM Enamelin, AMELX Amelogenin X, NA Not available, HWE Hardy-Weinberg equilibrium
aGenotypes: AA/AG/GG
bGenotypes: CC/CT/TT. i: 5-year-olds. ii: 13-year-olds