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. 2020 May 6;15:98. doi: 10.1186/s13014-020-01552-0

Table 3.

Univariate analysis for contralateral hippocampus failure

Variables cHC failure-free ratea Pb cHC + 1 cm failure-free ratea Pb
6 months (%) 12 months (%) 6 months (%) 12 months (%)
All patients 98.7 ± 1.3 97.2 ± 1.9 98.8 ± 1.2 93.4 ± 3.3
MGMT promoter methylation 0.868 0.628
Yes 100.0 100.0 100.0 92.4 ± 5.1
No 97.6 ± 2.4 94.7 ± 3.6 97.8 ± 2.2 94.9 ± 3.5
IDH1 mutation 0.080 0.234
Yes 100.0 100.0 100.0 100.0
No 98.6 ± 1.3 97.1 ± 2.0 98.7 ± 1.3 93.0 ± 3.5
Surgery 0.594 0.790
GTR 97.1 ± 2.9 97.1 ± 2.9 97.1 ± 2.9 92.8 ± 5.0
PR 100.0 100.0 100.0 95.5 ± 4.4
Biopsy 100.0 91.7 ± 8.0 100.0 91.7 ± 8.0
Subventricular zone involvement 0.034 0.113
Yes 97.9 ± 2.1 95.5 ± 3.1 98.0 ± 2.0 91.8 ± 4.8
No 100.0 100.0 100.0 95.7 ± 4.3
Spatial relationship to the subventricular zone [19] 0.196 0.211
Group I 97.1 ± 2.9 93.8 ± 4.2 97.1 ± 2.9 88.3 ± 6.7
Group II 100.0 100.0 100.0 100.0
Group III 100.0 100.0 100.0 100.0
Group IV 100.0 100.0 100.0 75.0 ± 21.7

Abbreviations: cHC contralateral hippocampus, MGMT methylated O6-methylguanine-DNA methyltransferase, IDH1 mutated isocitrate dehydrogenase 1, GTR gross total resection, PR partial resection

aFailure rates are displayed with standard errors

bLog-rank test