Table 1.
Demographics, schistosome counts and biochemical variables before treatment
| Variable | Normal Ranges | Schistosome positive n = 28 |
Schistosome negative n = 53 | p value |
|---|---|---|---|---|
| Male% | 78.6 | 81.1 | ||
| Age (years) | 15.0 (12.5, 21.5) | 16.0 (13.0, 22.0) | 0.547 | |
| Sh count (/10 mL) | 3.0 (2.0, 11.0) | 0 | 0.033 | |
| Albumin (g/L) | 35–55 | 51.9 (48.5, 53.0) | 55.9 (52.1, 61.5) | 0.003 |
| Globulin | 20–35 | 36.7 (32.8, 40.1) | 30.5 (22.4, 33.8) | 0.005 |
| Bilirubin (Direct) (μmol/L) | 0–5 | 5.7 (3.4, 7.5) | 5.7 (4.5, 7.1) | 0.825 |
| Bilirubin (Total) (μmol/L) | 3–22 | 14.1 (11.4, 20.2) | 14.8 (12.4, 19.2) | 0.809 |
| Creatinine (μmol/L) | 50–110 | 99.0 (77.0, 116.0) | 91.0 (75.0, 114.0) | 0.587 |
| GGT (U/L) | 9–48 | 20.0 (16.0, 26.0) | 24.0 (16.0, 33.0) | 0.243 |
| ALT (U/L) | 5–35 | 13.0 (9.0, 16.0) | 13.0 (9.0, 18.0) | 0.420 |
| AST (U/L) | 7–40 | 33.0 (28.0, 36.0) | 30.0 (25.0, 35.0) | 0.825 |
| AST/ALT ratio | 0.8 | 2.5 (1.9, 3.1) | 2.6 (2.0, 3.1) | 0.457 |
| Protein (g/L) | 60–80 | 89.0 (82.0, 92.0) | 87.0 (80.0, 91.0) | 0.840 |
| Urea (mmol/L) | 2.9–8.2 | 2.7 (2.1, 3.1) | 2.6 (2.1, 3.0) | 0.344 |
| eGFR (CKDEPI) | > 90 | 96.0 (80.0, 116.0) | 101.0 (88.0, 127.0) | 0.600 |
| eGFR (4v-MDRD) | > 90 | 100.5 (82.5, 120.0) | 95.0 (83.0, 123.0) | 0.776 |
Sh S. haematobium egg. eGFR (ml/min/1.73m2), proportion reported as percentage (interquartile range), biochemical variables reported as median (interquartile ranges)