Figure 2.

Study endpoints. ^aP values will be derived using Pearson’s χ² test or Fisher’s exact test, as appropriate. ^bAnalysis of covariance models will be used, with treatment group as a factor and baseline value as a covariate; mixed models with repeated measurement will be performed as necessary. BILAG-2004, British Isles Lupus Assessment Group-2004; CLASI, Cutaneous Lupus Erythematosus Disease Area and Severity Index; PGA, Physician’s Global Assessment; QOL, quality of life; SFI, Safety of Estrogens in Lupus Erythematosus National Assessment Flare Index; SLEDAI-2K, SLE Disease Activity Index-2000; SRI-4, SLE Responder Index-4; WPAI, Work Productivity and Activity Impairment.