Table 3. Comparison of ROC curve analysis of multivariate logistic regression models for the prediction of benign versus malignant thyroid nodules.

Combination model	Sensitivity (%)	Specificity (%)	AUC (95% CI)
2D_US	87.65	66.96	0.841 [0.786–0.896]
2D_US+CEUS	88.89	93.91	0.960 [0.935–0.986]
2D_US +E_mean	92.59	87.83	0.954 [0.925–0.982]
2D_US+CEUS+E_mean	96.30	90.04	0.985 [0.971–0.999]

Note:

ROC, receiver operating characteristic; AUC, the area under ROC curve; 2D_US, two dimensional ultrasound; CEUS, contrast enhance ultrasound; SWE, shear wave elastography; 95% CI, 95% confidence interval.