Figure 17.
A) RhoGEF inhibitors that are highly reactive or contain a PAIN motif (red). Toxicophores of reactive motifs are shown in purple. B) C21, inhibitor of DOCK5, a DHR RhoGEF.
A) RhoGEF inhibitors that are highly reactive or contain a PAIN motif (red). Toxicophores of reactive motifs are shown in purple. B) C21, inhibitor of DOCK5, a DHR RhoGEF.