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Distribution of variants in PTM motifs. (A) Number of motif-associated variants (MAVs) in each category (polymorphic, disease-related, or unclassified). (B) Motif-associated variants as observed in disease class of proteins and their occurrence in crosstalk motifs (in situ). (C) Number of MAVs observed at different positions in the PTM motif. (D) Proportion of MAVs in crosstalk/PTM motifs for each PTM type.
