Table 4:

Univariate Essential Elements Analysis of the Mother Cohorts

Element	Univariate Test	ASD mean in μg/mL	TD mean in μg/mL	ASD SD	TD SD	% TD Below Detection limit	% ASD Below Detection limit	Ratio ASD/TD	P-value	AUROC	False Discovery Rate
Boron	Mann-Whitney	1.52	1.34	8.81E-01	7.29E-01	0	0	1.14	0.44	0.56
Calcium	Equal Variance t-test	1.14E+02	91.5	72.9	59.6	0	0	1.24	0.22	0.58
Chromium	Mann-Whitney	2.95E-04	3.43E-04	1.06E-04	1.16E-04	96.6	100	8.63E-01	0.13	0.60
Cobalt	Mann-Whitney	8.77E-04	1.06E-03	3.45E-04	5.26E-04	69.0	82.1	8.31E-01	0.17	0.60
Copper	Mann-Whitney	1.05E-02	9.86E-03	3.47E-03	6.92E-03	0	0	1.06	7.5E-02	0.64
Iron	Mann-Whitney	2.22E-01	1.86E-01	1.30E-01	9.54E-02	31.0	25.0	1.20	0.31	0.58
Lithium	Mann-Whitney	6.23E-02	6.97E-02	4.40E-02	5.35E-02	0	0	8.93E-01	0.60	0.54
Magnesium	Equal Variance t-test	7.37E+01	6.63E+01	2.26E+01	2.66E+01	0	0	1.11	0.26	0.63
Manganese	Mann-Whitney	1.02E-03	8.48E-04	5.00E-04	4.62E-04	6.9	0	1.20	0.14	0.61
Molybdenum	Mann-Whitney	3.99E-02	5.01E-02	2.97E-02	2.58E-02	0	0	7.95E-01	6.5E-02	0.64
Phosphorus	Equal Variance t-test	592	658	218	200	0	0	9.00E-01	0.24	0.60
Potassium	Mann-Whitney	25.8	24.4	11.9	10.6	0	0	1.05	0.71	0.53
Selenium	Equal Variance t-test	4.81E-02	4.86E-02	1.26E-02	1.64E-02	0	0	9.90E-01	0.90	0.52
Sodium	Mann-Whitney	94.6	86.8	57.6	51.4	0	0	1.09	0.53	0.55
Strontium	Equal Variance t-test	1.44E-01	1.24E-01	8.01E-02	5.91E-02	0	0	1.16	0.28	0.55
Sulfur	Mann-Whitney	559	510	251	188	0	0	1.10	0.40	0.57
Vanadium	Mann-Whitney	2.32E-04	2.45E-04	1.03E-04	6.92E-05	79.3	78.6	9.44E-01	0.26	0.58
Zinc	Mann-Whitney	3.15E-01	3.01E-01	2.06E-01	1.60E-01	0	0	1.04	0.94	0.51

No FDR is computed as no element resulted in p < 0.05.