Skip to main content
. 2020 Apr 9;5(7):e134564. doi: 10.1172/jci.insight.134564

Figure 2. PM tumors are characterized by a homogeneous, small nest architectural pattern with a highly vascular network and infrequent inflammatory cells.

Figure 2

(A) Pie charts showing the distribution of architectures in primary tumors of patients with PM (n = 12) and reference pathology cohorts: patients without metastases (n = 431), and patients with non-PM metastases (n = 110). (B) H&E sections and IHC for PBRM1 and CD31 of PM as well as H&E sections of corresponding primary tumors. Pie charts of architectures corresponding to patients are shown below. (C) Architectural subtypes associated with more aggressive ccRCC. PM, pancreatic metastases; ccRCC, clear cell renal cell carcinoma.