Table 2. Pairwise comparisons of gray matter volume between SZ, BD, and HC groupsa.
| Anatomical region | Side | T max | Peak coordinates (MNI) | Cluster size (mm3) | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| SZ vs. HC | ||||||
| Thalamus | L/R | 5.812 | 0 | -19 | 7 | 5268 |
| Middle orbital gyrus | R | 6.476 | 4 | 47 | -2 | 2464 |
| Inferior frontal gyrus | L | 6.597 | -39 | 17 | -14 | 2440 |
| Anterior cingulate Cortex | L | 6.283 | -39 | 17 | -14 | 1252 |
| Insular lobe | L | 6.007 | -38 | 5 | 3 | 864 |
| Medial frontal gyrus | L | 5.641 | -2 | 48 | 22 | 611 |
| Caudate nucleus | L | 5.839 | -6 | 18 | -6 | 513 |
| Olfactory cortex | R | 5.682 | 27 | 8 | -14 | 398 |
| Insular lobe | R | 5.862 | 38 | 18 | -15 | 375 |
| Angular gyrus | L | 5.351 | -45 | -67 | 28 | 314 |
| Inferior frontal gyrus | R | 5.621 | 54 | 14 | 7 | 226 |
| Caudate nucleus | R | 5.352 | 9 | 20 | -5 | 169 |
| Hippocampus | R | 5.614 | 30 | -9 | -17 | 101 |
| Middle orbital gyrus | L | 5.360 | 2 | 59 | -14 | 101 |
| Inferior frontal gyrus | L | 5.494 | -46 | 9 | 28 | 94 |
| Inferior frontal gyrus | R | 5.511 | 50 | 14 | 30 | 88 |
| Inferior frontal gyrus | L | 5.634 | -48 | 29 | 19 | 84 |
| BD vs. HC | ||||||
| Thalamus | R | 5.285 | 8 | -12 | 1 | 155 |
| Insular lobe | L | 5.529 | -38 | 14 | -15 | 84 |
a Family-wise error corrected P < 0.017
That all MNI coordinates of maximum t values are selected in the significant region.
That there was no significant difference in gray matter volume between the SZ and BD groups.
Abbreviations: SZ, Schizophrenia. BD, Bipolar Disorder. HC, Healthy Control. MNI, Montreal Neurological Institute. L, Left. R, Right.