Table 3. Comparisons of diffusion indexes between SZ and HC groupsa.
Anatomical region | Side | T max | Peak coordinates (MNI) | Cluster size (mm3) | ||
---|---|---|---|---|---|---|
x | y | z | ||||
Fractional Anisotropy (FA) SZ vs. HC | ||||||
Anterior corona radiata | L | 5.424 | -18 | 34 | 16 | 2268 |
Posterior thalamic radiation | L | 4.878 | -26 | -62 | 15 | 481 |
Fornix (cres) | L | 4.806 | -28 | -25 | -8 | 370 |
Anterior limb of internal capsule | R | 4.557 | 21 | 19 | 7 | 353 |
Anterior corona radiata | R | 3.975 | 13 | 32 | -8 | 339 |
Body of corpus callosum | 5.247 | 7 | 11 | 24 | 336 | |
Fornix (column and body) | 4.666 | 0 | -1 | 15 | 293 | |
Retrolenticular part of internal capsule | L | 4.983 | -29 | -22 | 0 | 287 |
Body of corpus callosum | 5.212 | 9 | -28 | 25 | 255 | |
External capsule | R | 4.054 | 28 | 19 | 2 | 130 |
Splenium of corpus callosum | 3.853 | -5 | -37 | 20 | 121 | |
Sagittal stratum | L | 4.060 | -39 | -44 | -7 | 118 |
Splenium of corpus callosum | 4.543 | 26 | -53 | 15 | 109 | |
Anterior limb of internal capsule | L | 4.304 | -21 | 10 | 13 | 100 |
Retrolenticular part of internal capsule | R | 4.815 | 34 | -30 | 5 | 96 |
Anterior limb of internal capsule | L | 3.557 | -20 | 18 | 4 | 83 |
Axial Diffusivity (AD) SZ vs. HC | ||||||
Posterior corona radiata | R | 4.4447 | 28 | -31 | 19 | 541 |
Superior longitudinal fasciculus | R | 3.4658 | 37 | -16 | 27 | 127 |
Posterior limb of internal capsule | R | 3.5328 | 20 | -6 | 9 | 84 |
Superior longitudinal fasciculus | L | 4.3845 | -41 | -9 | 26 | 80 |
Radial Diffusivity (RD) SZ vs. HC | ||||||
Superior corona radiata | L | 6.0182 | -17 | -9 | 39 | 3218 |
Body of corpus callosum | 5.3067 | 10 | 13 | 24 | 1219 | |
Retrolenticular part of internal capsule | L | 4.9983 | -30 | -24 | -1 | 602 |
Retrolenticular part of internal capsule | R | 5.2397 | 37 | -33 | 5 | 463 |
Fornix (cres) | L | 4.6318 | -27 | -26 | -8 | 183 |
Posterior corona radiata | L | 4.6159 | -27 | -36 | 25 | 142 |
Splenium of corpus callosum | 4.6734 | 26 | -53 | 15 | 141 | |
Anterior limb of internal capsule | L | 3.9972 | -20 | 18 | 4 | 93 |
External capsule | R | 3.9933 | 29 | 15 | 3 | 90 |
Posterior thalamic radiation | R | 3.9213 | 35 | -62 | 1 | 87 |
Mean Diffusivity (MD) SZ vs. HC | ||||||
Superior corona radiata | L | 5.7383 | -18 | 16 | 36 | 3726 |
Posterior corona radiata | L | 5.036 | -26 | -34 | 27 | 1078 |
Anterior corona radiata | L | 4.9447 | -17 | 39 | -1 | 752 |
Posterior corona radiata | R | 4.2994 | 28 | -41 | 25 | 314 |
Anterior corona radiata | R | 4.8575 | 25 | 23 | 7 | 305 |
Superior longitudinal fasciculus | R | 4.0915 | 38 | -14 | 29 | 293 |
Sagittal stratum | L | 4.8634 | -40 | -42 | -7 | 141 |
Retrolenticular part of internal capsule | L | 3.8339 | -33 | -33 | 7 | 132 |
Superior longitudinal fasciculus | L | 5.5257 | -40 | -42 | 13 | 112 |
External capsule | R | 5.6883 | 32 | 11 | -1 | 103 |
Posterior limb of internal capsule | R | 3.8928 | 25 | -7 | 18 | 92 |
a Family-wise error corrected P < 0.017
That all MNI coordinates of maximum t values are selected in the significant region.
Abbreviations: SZ, Schizophrenia. HC, Healthy Control. MNI, Montreal Neurological Institute. L, Left. R, Right.