Table 4. Comparisons of diffusion indexes between BD and HC groupsa.
| Anatomical region | Side | T max | Peak coordinates (MNI) | Cluster size (mm3) | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Fractional Anisotropy (FA) BD vs. HC | ||||||
| Body of corpus callosum | 6.409 | -9 | 17 | 22 | 5205 | |
| Posterior thalamic radiation | L | 5.472 | -26 | -67 | 15 | 605 |
| Anterior limb of internal capsule | R | 4.911 | 21 | 19 | 5 | 488 |
| External capsule | R | 4.918 | 29 | 15 | 3 | 412 |
| Splenium of corpus callosum | 4.084 | 25 | -52 | 22 | 338 | |
| External capsule | L | 3.701 | -30 | 10 | -8 | 296 |
| Cingulum | L | 4.127 | -10 | -20 | 34 | 155 |
| Posterior corona radiata | L | 4.393 | -26 | -29 | 26 | 138 |
| Fornix (cres) | L | 4.551 | -26 | -32 | -3 | 97 |
| Retrolenticular part of internal capsule | R | 3.906 | 30 | -20 | -1 | 97 |
| Fornix (cres) | R | 4.822 | 28 | -27 | -6 | 92 |
| Axial Diffusivity (AD) BD vs. HC | ||||||
| Superior corona radiata | R | 4.2171 | 24 | -8 | 37 | 381 |
| Posterior limb of internal capsule | R | 3.6601 | 26 | -20 | 12 | 134 |
| Superior corona radiata | L | 5.0367 | -27 | 1 | 31 | 106 |
| Posterior limb of internal capsule | R | 4.465 | 26 | -8 | 18 | 83 |
| Radial Diffusivity (RD) BD vs. HC | ||||||
| Body of corpus callosum | 5.992 | -10 | 17 | 23 | 8506 | |
| External capsule | R | 5.048 | 29 | 16 | 3 | 1163 |
| Posterior thalamic radiation | L | 5.752 | -26 | -67 | 15 | 533 |
| Retrolenticular part of internal capsule | R | 4.572 | 35 | -29 | 5 | 442 |
| Posterior corona radiata | L | 4.697 | -26 | -32 | 25 | 356 |
| Cingulum | L | 5.137 | -9 | -35 | 33 | 223 |
| Superior corona radiata | R | 4.51 | 27 | -14 | 33 | 183 |
| Cingulum | R | 4.478 | 12 | -50 | 18 | 118 |
| Retrolenticular part of internal capsule | L | 3.43 | -32 | -28 | 4 | 97 |
| Mean Diffusivity (MD) BD vs. HC | ||||||
| Superior corona radiata | L | 5.744 | -18 | -3 | 41 | 5391 |
| Superior corona radiata | R | 5.77 | 28 | 7 | 28 | 1844 |
| Superior longitudinal fasciculus | L | 5.232 | -35 | -41 | 31 | 971 |
| Anterior corona radiata | R | 4.659 | 18 | 37 | 7 | 737 |
| Posterior thalamic radiation | R | 4.17 | 29 | -57 | 17 | 635 |
| Posterior corona radiata | R | 4.744 | 29 | -44 | 26 | 520 |
| Body of corpus callosum | 4.648 | 12 | -28 | 27 | 189 | |
| Anterior limb of internal capsule | R | 3.808 | 21 | 19 | 6 | 137 |
| External capsule | R | 5.081 | 31 | 12 | -2 | 129 |
| Superior longitudinal fasciculus | R | 4.949 | 33 | 2 | 20 | 99 |
| External capsule | L | 4.173 | -24 | 21 | 3 | 91 |
a Family-wise error corrected P < 0.017
That all MNI coordinates of maximum t values are selected in the significant region.
Abbreviations: BD, Bipolar Disorder. HC, Healthy Control. MNI, Montreal Neurological Institute. L, Left. R, Right.