Table 1.
Variable | Baseline analysis |
Survival analysis |
|||
---|---|---|---|---|---|
Controls (n = 301) | Alzheimer’s disease (n = 187) | Controls (n = 273) | Mild cognitive impairment (n = 350) | Alzheimer’s disease (n = 424) | |
Age, mean (SD) | 75.49 (5.23) | 75.67 (7.92) | 78.82 (6.78) | 77.83 (7.7) | 74.77 (8.14) |
Female, n (%) | 135 (44.85) | 82 (43.85) | 126 (46.15) | 134 (38.29) | 172 (40.57) |
Education, mean (SD) | 16.3 (2.72) | 14.96 (2.98) | 16.44 (2.72) | 15.84 (2.82) | 15.42 (2.91) |
APOE, n (%) | |||||
ε3/ε3 | 201 (60.54) | 60 (29.41) | 172 (63) | 183 (52.29) | 140 (33.02) |
ε4+ | 92 (27.71) | 139 (68.14) | 69 (25.27) | 139 (39.71) | 278 (65.57) |
ε2+ | 39 (11.75) | 5 (2.45) | 32 (11.72) | 28 (8) | 6 (1.42) |
nMT-PRS, mean (SD) | −0.37 (0.85) | 0.47 (0.93) | −0.38 (0.86) | −0.08 (0.82) | 0.4 (0.94) |
Haplogroups, n (%) | |||||
H | 169 (50.9) | 92 (45.1) | 130 (47.62) | 151 (43.14) | 200 (47.17) |
I | 14 (4.22) | 6 (2.94) | 10 (3.66) | 10 (2.86) | 17 (4.01) |
J | 29 (8.73) | 20 (9.8) | 25 (9.16) | 36 (10.29) | 38 (8.96) |
K | 34 (10.24) | 31 (15.2) | 28 (10.26) | 46 (13.14) | 43 (10.14) |
T | 31 (9.34) | 16 (7.84) | 23 (8.42) | 40 (11.43) | 41 (9.67) |
U | 35 (10.54) | 26 (12.75) | 35 (12.82) | 48 (13.71) | 51 (12.03) |
V | 11 (3.31) | 7 (3.43) | 13 (4.76) | 10 (2.86) | 14 (3.3) |
W | 3 (0.9) | 4 (1.96) | 3 (1.1) | 7 (2) | 10 (2.36) |
X | 6 (1.81) | 2 (0.98) | 6 (2.2) | 2 (0.57) | 10 (2.36) |