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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Neurobiol Aging. 2019 Sep 24;87:138.e7–138.e14. doi: 10.1016/j.neurobiolaging.2019.09.007

Table 1.

Descriptive characteristics of Alzheimer’s Disease Neuroimaging Initiative at baseline and last assessment (survival analysis)

Variable Baseline analysis
Survival analysis
Controls (n = 301) Alzheimer’s disease (n = 187) Controls (n = 273) Mild cognitive impairment (n = 350) Alzheimer’s disease (n = 424)
Age, mean (SD) 75.49 (5.23) 75.67 (7.92) 78.82 (6.78) 77.83 (7.7) 74.77 (8.14)
Female, n (%) 135 (44.85) 82 (43.85) 126 (46.15) 134 (38.29) 172 (40.57)
Education, mean (SD) 16.3 (2.72) 14.96 (2.98) 16.44 (2.72) 15.84 (2.82) 15.42 (2.91)
APOE, n (%)
 ε3/ε3 201 (60.54) 60 (29.41) 172 (63) 183 (52.29) 140 (33.02)
 ε4+ 92 (27.71) 139 (68.14) 69 (25.27) 139 (39.71) 278 (65.57)
 ε2+ 39 (11.75) 5 (2.45) 32 (11.72) 28 (8) 6 (1.42)
 nMT-PRS, mean (SD) −0.37 (0.85) 0.47 (0.93) −0.38 (0.86) −0.08 (0.82) 0.4 (0.94)
Haplogroups, n (%)
 H 169 (50.9) 92 (45.1) 130 (47.62) 151 (43.14) 200 (47.17)
 I 14 (4.22) 6 (2.94) 10 (3.66) 10 (2.86) 17 (4.01)
 J 29 (8.73) 20 (9.8) 25 (9.16) 36 (10.29) 38 (8.96)
 K 34 (10.24) 31 (15.2) 28 (10.26) 46 (13.14) 43 (10.14)
 T 31 (9.34) 16 (7.84) 23 (8.42) 40 (11.43) 41 (9.67)
 U 35 (10.54) 26 (12.75) 35 (12.82) 48 (13.71) 51 (12.03)
 V 11 (3.31) 7 (3.43) 13 (4.76) 10 (2.86) 14 (3.3)
 W 3 (0.9) 4 (1.96) 3 (1.1) 7 (2) 10 (2.36)
 X 6 (1.81) 2 (0.98) 6 (2.2) 2 (0.57) 10 (2.36)