Table 4.

Glucose, insulin, NEFA kinetics during IVGTT

Variables	20°C		35°C		SED	P-values
	Control (n = 9)	Cr (n = 9)	Control (n = 9)	Cr (n = 9)		Temperature	Diet	Interaction
Glucose fasting, mM	7.89	7.94	7.67	7.50	0.489	0.29	0.89	0.79
Glucose peak, mM	12.4	11.6	11.1	11.2	0.70	0.10	0.52	0.35
Glucose AUC60min, mM min	39.4	44.0	55.7	77.3	20.36	0.094	0.37	0.56
Glucose clearance rate (slope2–60min), mM min−1	0.21	0.17	0.13	0.13	0.039	0.035	0.36	0.38
Insulin fasting, μU/mL	2.15	1.77	1.78	1.58	0.0240	0.10	0.094	0.61
Insulin peak, μU/mL	16.9	16.6	14.6	12.9	1.60	0.012	0.38	0.55
Insulin AUC10 min, μU mL−1min	109	109	90	80	11.7	0.006	0.56	0.58
Insulin AUC60 min, μU mL−1min	144	170	177	176	20.4	0.19	0.39	0.36
Insulin acute release rate (slope0–10min), μU mL−1min−1	0.73	0.77	0.49	0.64	0.122	0.045	0.27	0.53
Insulin clearance rate (slope0–60min), μU mL−1min−1	0.15	0.17	0.15	0.15	0.030	0.65	0.60	0.52
HOMA-Insulin Resistance	0.76	0.56	0.54	0.47	0.073	0.007	0.013	0.21
NEFA fasting, μM	463	520	853	716	155.7	0.015	0.72	0.39
NEFA minimum, μM	167	203	231	186	47.7	0.50	0.89	0.24
NEFA AUC30min, μM min	-3987	-3356	-9239	-8352	2355	0.006	0.70	0.95
NEFA AUC60min, μM min	-2223	-1743	-22882	-17512	5639	< 0.001	0.47	0.55
NEFA decrease rate (slope2–30min), μM min−1	12.0	14.8	23.6	19.2	4.14	0.013	0.80	0.20
NEFA decrease rate (slope30–60min), μM min−1	6.5	8.7	1.6	4.4	1.85	0.002	0.068	0.84