Table 3.
Changes in cognitive scores according to systolic inter-arm blood pressure difference
| Cognitive score | IAD <5 mmHg, n (95% CI) | IAD ≥5 mmHg, n (95% CI) | P-value | IAD <10 mmHg, n (95% CI) | IAD ≥10 mmHg, n (95% CI) | P-value |
|---|---|---|---|---|---|---|
| Change in MMSE score, units | 2.17 (1.78 to 2.56) | 2.91 (2.08 to 3.73) | 0.084 | 2.25 (1.86 to 2.63) | 2.80 (1.89 to 3.72) | 0.237 |
| Rate of change MMSE scorea | 0.29 (0.24 to 0.35) | 0.45 (0.32 to 0.58) | 0.012 | 0.31 (0.25 to 0.36) | 0.44 (0.29 to 0.59) | 0.052 |
| Change in Trails A score, seconds | 5.55 (2.47 to 8.63) | 5.68 (−1.35 to 12.70) | 0.970 | 5.77 (2.74 to 8.79) | 4.68 (−3.53 to 12.90) | 0.779 |
| Rate of change Trails A scorea | 0.75 (0.36 to 1.13) | 0.62 (−0.28 to 1.52) | 0.780 | 0.79 (0.39 to 1.16) | 0.42 (−0.61 to 1.45) | 0.463 |
| Change in Trails B score, seconds | 10.92 (6.03 to 15.80) | 2.96 (−6.46 to 12.38) | 0.130 | 10.66 (5.93 to 15.38) | 1.43 (−9.47 to 12.38) | 0.117 |
| Rate of change Trails B scorea | 1.26 (0.68 to 1.84) | 0.18 (−0.97 to 1.32) | 0.084 | 1.22 (0.66 to 1.78) | −0.0097 (−1.39 to 1.32) | 0.081 |
a
Change in unit score per year of follow-up. IAD = systolic inter-arm blood pressure difference. MMSE = mini mental state examination. Trails = Trail Making Tests.