Table 4.
Unadjusted and adjusted odds ratios for substantial cognitive decline for all participants according to systolic inter-arm blood pressure difference
| Cognitive measure | IAD ≥5 mmHg | IAD ≥10 mmHg | ||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted OR (95% CI) | P-value | Adjusteda OR (95% CI) | P-value | Unadjusted OR (95% CI) | P-value | Adjusteda OR (95% CI) | P-value | |
| MMSE | 1.41 (1.03 to 1.93) | 0.032 | 1.31 (0.91 to 1.88) | 0.140 | 1.30 (0.92 to 1.83) | 0.142 | 1.07 (0.72 to 1.60) | 0.740 |
| Trails A | 1.17 (0.80 to 1.70) | 0.415 | 1.10 (0.71 to 1.73) | 0.663 | 1.24 (0.82 to 1.86) | 0.305 | 1.05 (0.64 to 1.74) | 0.833 |
| Trails B | 1.30 (0.94 to 1.79) | 0.112 | 1.23 (0.80 to 1.89) | 0.344 | 1.27 (0.89 to 1.83) | 0.192 | 1.06 (0.66 to 1.73) | 0.800 |
| Composite outcome | 1.44 (1.10 to 1.89) | 0.009 | 1.46 (1.05 to 2.03) | 0.026 | 1.39 (1.03 to 1.88) | 0.030 | 1.23 (0.85 to 1.78) | 0.265 |
a
Adjusted for age, sex, baseline MMSE score, years in education, systolic blood pressure, ankle–brachial index, presence of diabetes, previous cerebrovascular event, and duration of follow-up. CI = confidence interval. IAD = systolic inter-arm blood pressure difference. MMSE = mini mental state examination. OR = odds ratio. Trails = Trail Making Tests.