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. Author manuscript; available in PMC: 2020 May 8.
Published in final edited form as: Subcell Biochem. 2017;83:323–347. doi: 10.1007/978-3-319-46503-6_12

Fig. 12.1.

Fig. 12.1

Architecture of cullin-RING ligases. (a) Schematic representation of the components of a CRL. (b) Specific protein factors for each CRL family. (c) Structural architecture of a CRL1 in ribbon representation generated from PDB IDs 1LDK and 1P22. (d) Organization of Cul1 CTD–Rbx1. The domains of Cul1 are labeled in (c) and (d). The Zn2+ ions in (c) and (d) are shown as gray spheres