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. 2020 Mar 24;24(9):5274–5289. doi: 10.1111/jcmm.15183

Figure 5.

Figure 5

SLC31A1 knock‐down abrogates the effect of PTBP1 silence on the chemosensitivity of CISR osteosarcoma cells. A, In MG‐63CISR and U‐2OSCISR cells, intracellular platinum concentration was determined by inductively coupled plasma mass spectrometry (ICP‐MS). B and C, CCK‐8 assay and colony formation assay determined the cell viability and colony formation ability of MG‐63CISR and U‐2OSCISR cells. D, Flow cytometric analysis of apoptosis was used to detect the effects of cisplatin alone. PTBP1 knock‐down combined with cisplatin, PTBP1 knock‐down combined with cisplatin simultaneously inhibited SLC31A1 on cell apoptosis. **P < .01