TABLE 2.

Gene expression profile in trabecular meshwork tissue in the study cohort

	POAG (mean ± SEM; median)	PACG (mean ± SEM; median)	P value
TGFβ1	0.038 ± 0.022; 0.003	0.011 ± 0.003; 0.005	.7466
TGFβ2	0.053 ± 0.028; 0.007	0.076 ± 0.052; 0.006	.7567
TGFβR2	0.135 ± 0.075; 0.033	0.057 ± 0.027; 0.013	.2379
CTGF	0.546 ± 0.218; 0.016	0.684 ± 0.334; 0.016	.7661
FN	0.023 ± 0.005; 0.016	0.037 ± 0.011; 0.005	.4314
LOXL2	0.012 ± 0.005; 0.004	0.009 ± 0.002; 0.004	.7874
WNT3A	0.121 ± 0.030; 0.042	0.048 ± 0.012; 0.010	.0566
HEVIN	2.487 ± 1.353; 0.024	7.737 ± 3.377; 0.025	.7914
DECORIN	0.085 ± 0.035; 0.012	0.351 ± 0.219; 0.020	.7032

Mann–Whitney test was used for statistical analysis.

Abbreviations: CTGF, connective tissue growth factor; DECORIN, DSPG2, dermatan sulphate proteoglycans II; FN, fibronectin; HEVIN, SPARCL1, secreted protein acidic and rich in cysteine‐like 1; LOXL2, lysyl oxidase–like 2; PACG, primary angle‐closure glaucoma; POAG, primary open‐angle glaucoma; SEM, standard error of mean; TGFβ1, transforming growth factor beta 1; TGFβ2, transforming growth factor beta 2; TGFβR2, transforming growth factor beta receptor 2; WNT3A, wingless‐type family member 3A.