TABLE 3.
Cohort characteristics of study subjects based on IOP‐lowering medications
| PG (mean ± SEM; median) | BB (mean ± SEM; median) | PG+BB (mean ± SEM; median) | P value (PG vs BB) | P value (PG vs PG+BB) | P value (BB vs PG+BB) | |
|---|---|---|---|---|---|---|
| Sample size | 14 | 28 | 27 | NA | NA | NA |
| Sex (M/F) | 7/7 | 23/5 | 18/9 | NA | NA | NA |
| Age (y) | 70.9 ± 1.2; 72 | 61.2 ± 1.7; 62 | 63.9 ± 2.2; 66 | .0006* | .0357* | .3362* |
| IOP (mm Hg) | 16.7 ± 0.9; 16 | 20.1 ± 1.3; 18 | 18.4 ± 1.3; 18 | .2336 † | .8328 † | .3063 † |
| MD | −15.4 ± 2.6; −14.6 | −23.5 ± 1.5; −24.1 | −20.57 ± 1.9; −23.4 | .0069* | .1218 † | .3447 † |
| PSD | 6.1 ± 0.9; 5.9 | 7.0 ± 0.5:7.2 | 6.7 ± 0.6:6.6 | .3588* | .5933* | .6748* |
| VFI score | 56.2 ± 8.1; 58 | 30.8 ± 5.3; 24 | 37.3 ± 6.7; 24 | .0173 † | .0576 † | .8996 † |
| Duration of IOP‐lowering medications (months) | 16.3 ± 4.9; 7.3 | 4.8 ± 1.4; 1.6 | 24.6 ± 4.3; 22 | .0512 † | .244* | <.0001 † |
Abbreviations: BB, beta‐blockers; IOP, intraocular pressure; MD, mean deviation; PG, prostaglandin analogues; PSD, pattern standard deviation; SEM, standard error of mean; VFI, visual field index.
*
Unpaired t test.
†
Mann–Whitney test.