Figure 2.

M2 macrophage‐derived exosomes promote proliferation, migration, invasion and tumour xenograft of PC cells and restrict their apoptosis. A, RT‐qPCR detection of lncRNA SBF2‐AS1 expression in PANC‐1 cells after Mp‐Exo treatment; B, EdU detection of changes in PANC‐1 cell proliferation after Mp‐Exo treatment (scale bar = 50 μm); C, detection of changes in PANC‐1 cell migration after treatment with Mp‐Exo by scratch test; D, detection of PANC‐1 cell invasion after Mp‐Exo treatment by Transwell assay (scale bar = 50 μm); E, apoptosis detection of PANC‐1 cells after treatment with Mp‐Exo by flow cytometry; F, representative figures of tumour xenograft in nude mice; G, tumour weight change in each group of nude mice (n = 8); H, tumour volume change in each group of nude mice (n = 8); *, P < .05 vs the control group; all the above results were measurement data expressed by mean ± standard deviation, and comparison between two groups was analysed by independent sample t test; the cell experiment was repeated three times