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. 2020 Mar 27;24(9):5363–5374. doi: 10.1111/jcmm.15192

Figure 6.

Figure 6

Six1 reintroduction rescues the TMZ‐resistant effect of miR‐155‐3p. A, Cell viability of A172 cells transfected with miR‐con or miR‐155‐3p with or without Six1 overexpression was treated with increasing dose of TMZ. B, Cell viability of U87 cells transfected with miR‐con or miR‐155‐3p with or without Six1 overexpression was treated with increasing dose of TMZ. C, Colony formation assay of A172 cells transfected with miR‐con or miR‐155‐3p with or without Six1 overexpression was treated with increasing dose of TMZ. D, Colony formation assay of U87 cells transfected with miR‐con or miR‐155‐3p with or without Six1 overexpression was treated with increasing dose of TMZ. E, Western blotting of cleaved caspase 3 of A172 cells transfected with miR‐con or miR‐155‐3p with or without the Six1 overexpression treated with 100 μmol/L TMZ for 48 h. F, Western blotting of cleaved caspase 3 of U87 cells transfected with miR‐con or miR‐155‐3p with or without the Six1 overexpression treated with 100 μmol/L TMZ for 48 h. Results were expressed as means ± SD of 3 independent experiments. **P < .01