Figure 7.

miR‐155‐3p inhibition sensitizes TMZ in vivo. A, U87 cells pre‐treated with a lentivirus expressing anti‐miR‐155‐3p or anti‐miR‐con were injected in both flank of nude mice. Tumour volume was calculated every two days. B, Tumour weight was analysed at end of the experiment. C, Western blotting of cleaved caspase 3 in indicated tumours. D, Western blotting of Six1 in indicated tumours. E, Representative immunohistochemical images of Ki‐67 in anti‐miR‐155‐3p and the anti‐miR‐con transfected tumours. Scale bar: 25μm. F, IF staining of cleaved caspase 3 in indicated tumours. Scale bar: 25μm