Figure 4.

circFBXO11/miR‐605 targets FOXO3. A, The potential target of circFBXO11/miR‐605 axis was predicted using the StarBase database (http://starbase.sysu.edu.cn/). B, Luciferase reporter assay indicated the luciferase activity of the transfection of miR‐605 and FOXO3 3’‐UTR wild‐type or mutant. C, RT‐PCR revealed the FOXO3 mRNA with miR‐605 mimics transfection or control. D, RT‐PCR showed the FOXO3 mRNA level with circFBXO11 overexpression or circFBXO11 knockdown transfection. E, The correlation between miR‐605 and circFBXO11 was calculated by Spearman's rank correlation coefficients. Data are the means ± SD. **P < .01