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Guaiacol inhibited osteoclast function and attenuated early osteoclastogenesis. A, Pit‐forming assay of osteoclasts and quantification of pit area. B, F‐actin ring formation by osteoclasts and quantification of actin rings. RAW264.7 cells were stimulated with M‐CSF and RANKL and treated with 0.25, 0.5 and 1.0 μmol/L guaiacol. C, Effect of 1.0 μmol/L guaiacol on the number of TRAP‐positive cells. **P < .01
