Table 3.

Univariate Poisson regression analysis

Gait speed					Cognitive status
1➔0					1➔0
Variable	Coefficient	Std. error	pvalue	95% CI	Variable	Coefficient	Std. error	pvalue	95%CI
Female					Female
Leptin	0.358	0.162	0.027	0.040–0.676	–
Lymphocytes	0.461	0.165	0.005	0.137–0.785
Insulin	0.281	0.122	0.022	0.041–0.521
Male					Male
Creatinine	− 0.654	0.263	0.013	− 1.169–0.138	Leptin	0.939	0.457	0.04	0.044–1.834
					Triglyceride	− 0.667	0.325	0.04	− 1.303–0.031
0➔0					0➔0
Female					Female
Leptin	− 0.173	0.073	0.018	− 0.317–0.029	HRT	0.210	0.092	0.023	0.028–0.389
Cholesterol	0.184	0.070	0.008	0.048–0.321	LDH	−0.423	0.108	0.000	−0.635 - 0.211
Weight	− 0.174	0.087	0.044	− 0.344–0.005
% Body fat	− 0.189	0.069	0.006	− 0.325–0.053
HDL	0.169	0.080	0.034	0.013–0.325
LDH	− 0.399	0.095	0.000	− 0.585–0.212
Soft tissue	− 0.199	0.085	0.019	− 0.366–0.033
Creatinine	0.250	0.104	0.017	0.062–0.455
Male					Male
Cholesterol	0.313	0.095	0.001	0.128–0.499	APSM	0.416	0.175	0.028	0.041–0.721
BMCWRD	− 0.220	0.110	0.046	− 0.436–0.003	LBM	0.381	0.174	0.017	0.074–0.759
					LDH	− 0.288	0.142	0.043	− 0.566–0.010
0➔1					0➔1
Female					Female
Leptin	0.456	0.225	0.043	0.014–0.898	Triglyceride	− 0.848	0.379	0.025	− 1.591–0.105
Male					Male
IGF1	0.566	0.226	0.012	0.123–1.009	–
Creatinine	− 0.550	0.270	0.042	− 1.080–0.021
Lymphocytes	− 0.572	0.291	0.049	− 1.141–0.002

Gait univariate analysis are adjusted for age and APOE4. Cognitive univariate analysis are adjusted for age, APOE4 and education. APOE4 apolipoprotein E4, HDL high-density lipoprotein cholesterol, LDH lactate dehydrogenase, BMCWRD bone mineral content Ward’s triangle, HRT hormone replacement therapy, APSM appendicular skeletal muscle mass, LBM lean body mass