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. 2020 May 7;10:45. doi: 10.1186/s13550-020-00635-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — [^99mTc]Tc-PSMA-I&S-SPECT/CT in primary high risk PCa. a 71-year-old man with Gleason 9 PCa (PSA 46 ng/ml). Apart from the primary tumor (green arrow), increased PSMA expression was detected in one lymph node in the right iliac region and in the left inguinal region (red arrows)(TxN1M0). b 77-year-old man with Gleason 9 PCa (PSA 80 ng/ml). PSMA expression was increased in the primary tumor only (green arrow), no metastases were detected (TxN0M0)