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[99mTc]Tc-PSMA-I&S-SPECT/CT of a 59-year-old patient with radical prostatovesiculectomy and salvage radiotherapy. According to morphological imaging 2 years later osseous metastases were suspected. a At baseline, multiple osseous and lymph node metastases (partly marked with red arrows) were detected with mostly mild PSMA expression (PSA 4.75 ng/ml). b Follow-up scan 4 months later under antihormonal therapy (PSA 0.01 ng/ml). [99mTc]Tc-PSMA-I&S-SPECT/CT was negative
